eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | osteopetrosis |
| Symptom | C0018952|extramedullary hematopoiesis |
| Sentences | 2 |
| PubMedID- 22351931 | Interestingly, mice lacking ocl activity develop severe osteopetrosis, whch is associated with extramedullary hematopoiesis, suggesting that ocls may participate not only in the regulation or maintenance but also in the initial formation of the hsc niche (dougall et al., 1999; kong et al., 1999; tagaya et al., 2000; blin-wakkach et al., 2004b). |
| PubMedID- 24708266 | In summary, gross and histopathological lesions included long bone osteopetrosis with subsequent extramedullary hematopoiesis and lymphoid depletion. |
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